The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.

Analysis of pathological data in the 10th year of follow-up of a multicentre trial of the management of operable breast cancer has confirmed the correlation of prognosis with tumour grade, tumour size and lymph-node status. For each factor examined there was no difference in survival between the 2 t...

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Detalles Bibliográficos
Autores principales: Elston, C. W., Gresham, G. A., Rao, G. S., Zebro, T., Haybittle, J. L., Houghton, J., Kearney, G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011009/
https://www.ncbi.nlm.nih.gov/pubmed/7044401
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author Elston, C. W.
Gresham, G. A.
Rao, G. S.
Zebro, T.
Haybittle, J. L.
Houghton, J.
Kearney, G.
author_facet Elston, C. W.
Gresham, G. A.
Rao, G. S.
Zebro, T.
Haybittle, J. L.
Houghton, J.
Kearney, G.
author_sort Elston, C. W.
collection PubMed
description Analysis of pathological data in the 10th year of follow-up of a multicentre trial of the management of operable breast cancer has confirmed the correlation of prognosis with tumour grade, tumour size and lymph-node status. For each factor examined there was no difference in survival between the 2 treatment groups ("watch policy" and radiotherapy) but patients in the WP group whose tumours were of Grade II or III or greater than 2 cm, or with lymph-node metastases, had a greater chance of local recurrence. Cellular reaction had no relationship with prognosis, except in patients with Grade III tumours. The clinical relevance and application of these results are discussed.
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spelling pubmed-20110092009-09-10 The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects. Elston, C. W. Gresham, G. A. Rao, G. S. Zebro, T. Haybittle, J. L. Houghton, J. Kearney, G. Br J Cancer Research Article Analysis of pathological data in the 10th year of follow-up of a multicentre trial of the management of operable breast cancer has confirmed the correlation of prognosis with tumour grade, tumour size and lymph-node status. For each factor examined there was no difference in survival between the 2 treatment groups ("watch policy" and radiotherapy) but patients in the WP group whose tumours were of Grade II or III or greater than 2 cm, or with lymph-node metastases, had a greater chance of local recurrence. Cellular reaction had no relationship with prognosis, except in patients with Grade III tumours. The clinical relevance and application of these results are discussed. Nature Publishing Group 1982-05 /pmc/articles/PMC2011009/ /pubmed/7044401 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Elston, C. W.
Gresham, G. A.
Rao, G. S.
Zebro, T.
Haybittle, J. L.
Houghton, J.
Kearney, G.
The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title_full The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title_fullStr The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title_full_unstemmed The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title_short The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects.
title_sort cancer research campaign (king's/cambridge trial for early breast cancer: clinico-pathological aspects.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011009/
https://www.ncbi.nlm.nih.gov/pubmed/7044401
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