The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.

Radiolabelled affinity-purified antibody to carcinoembryonic antigen (CEA) was injected i.v. into immune-suppressed mice carrying xenografts of human breast carcinoma. Its distribution in the tumours was examined by a combination of immunocytochemistry and autoradiography. The antibody interacted pr...

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Autores principales: Moshakis, V., Ormerod, M. G., Westwood, J. H., Imrie, S., Neville, A. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011056/
https://www.ncbi.nlm.nih.gov/pubmed/7104194
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author Moshakis, V.
Ormerod, M. G.
Westwood, J. H.
Imrie, S.
Neville, A. M.
author_facet Moshakis, V.
Ormerod, M. G.
Westwood, J. H.
Imrie, S.
Neville, A. M.
author_sort Moshakis, V.
collection PubMed
description Radiolabelled affinity-purified antibody to carcinoembryonic antigen (CEA) was injected i.v. into immune-suppressed mice carrying xenografts of human breast carcinoma. Its distribution in the tumours was examined by a combination of immunocytochemistry and autoradiography. The antibody interacted predominantly with the CEA in the extracellular tumour space, rather than on the cell membrane or cytoplasm. IMAGES:
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spelling pubmed-20110562009-09-10 The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach. Moshakis, V. Ormerod, M. G. Westwood, J. H. Imrie, S. Neville, A. M. Br J Cancer Research Article Radiolabelled affinity-purified antibody to carcinoembryonic antigen (CEA) was injected i.v. into immune-suppressed mice carrying xenografts of human breast carcinoma. Its distribution in the tumours was examined by a combination of immunocytochemistry and autoradiography. The antibody interacted predominantly with the CEA in the extracellular tumour space, rather than on the cell membrane or cytoplasm. IMAGES: Nature Publishing Group 1982-07 /pmc/articles/PMC2011056/ /pubmed/7104194 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Moshakis, V.
Ormerod, M. G.
Westwood, J. H.
Imrie, S.
Neville, A. M.
The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title_full The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title_fullStr The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title_full_unstemmed The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title_short The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.
title_sort site of binding of anti-cea antibodies to tumour cea in vivo: an immunocytochemical and autoradiographic approach.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011056/
https://www.ncbi.nlm.nih.gov/pubmed/7104194
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