Tumour lysis as a factor affecting blood levels of CEA.

A hypothesis is proposed that tumour lysis may be an important factor affecting blood levels of CEA. This has been explored in an experimental study with a model tumour system, consisting of immune-deprived mice bearing human CEA-producing tumours. Using agents such as irradiation, chemotherapeutic...

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Detalles Bibliográficos
Autor principal: Quayle, J. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011095/
https://www.ncbi.nlm.nih.gov/pubmed/6817775
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author Quayle, J. B.
author_facet Quayle, J. B.
author_sort Quayle, J. B.
collection PubMed
description A hypothesis is proposed that tumour lysis may be an important factor affecting blood levels of CEA. This has been explored in an experimental study with a model tumour system, consisting of immune-deprived mice bearing human CEA-producing tumours. Using agents such as irradiation, chemotherapeutic drugs, diphtheria toxin and techniques such as cryosurgery, it has been shown that tumour lysis is important when it is both rapid and extensive. The extent to which this may occur in patients remains uncertain, except in rare instances of dramatic response of malignant disease to treatment.
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spelling pubmed-20110952009-09-10 Tumour lysis as a factor affecting blood levels of CEA. Quayle, J. B. Br J Cancer Research Article A hypothesis is proposed that tumour lysis may be an important factor affecting blood levels of CEA. This has been explored in an experimental study with a model tumour system, consisting of immune-deprived mice bearing human CEA-producing tumours. Using agents such as irradiation, chemotherapeutic drugs, diphtheria toxin and techniques such as cryosurgery, it has been shown that tumour lysis is important when it is both rapid and extensive. The extent to which this may occur in patients remains uncertain, except in rare instances of dramatic response of malignant disease to treatment. Nature Publishing Group 1982-08 /pmc/articles/PMC2011095/ /pubmed/6817775 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Quayle, J. B.
Tumour lysis as a factor affecting blood levels of CEA.
title Tumour lysis as a factor affecting blood levels of CEA.
title_full Tumour lysis as a factor affecting blood levels of CEA.
title_fullStr Tumour lysis as a factor affecting blood levels of CEA.
title_full_unstemmed Tumour lysis as a factor affecting blood levels of CEA.
title_short Tumour lysis as a factor affecting blood levels of CEA.
title_sort tumour lysis as a factor affecting blood levels of cea.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011095/
https://www.ncbi.nlm.nih.gov/pubmed/6817775
work_keys_str_mv AT quaylejb tumourlysisasafactoraffectingbloodlevelsofcea

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