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The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring

BACKGROUND: Studies on heteroplasmy occurring in the mitochondrial DNA (mtDNA) control region (CR) in leukocytes of centenarians and younger subjects have shown that the C150T somatic transition is over-represented in centenarians. However, whether the occurrence/accumulation of heteroplasmy is a ph...

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Detalles Bibliográficos
Autores principales:	Rose, Giuseppina, Passarino, Giuseppe, Scornaienchi, Vittorio, Romeo, Giuseppe, Dato, Serena, Bellizzi, Dina, Mari, Vincenzo, Feraco, Emidio, Maletta, Raffaele, Bruni, Amalia, Franceschi, Claudio, De Benedictis, Giovanna
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014781/ https://www.ncbi.nlm.nih.gov/pubmed/17727699 http://dx.doi.org/10.1186/1471-2164-8-293

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