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Inconsistencies in Neanderthal Genomic DNA Sequences

Two recently published papers describe nuclear DNA sequences that were obtained from the same Neanderthal fossil. Our reanalyses of the data from these studies show that they are not consistent with each other and point to serious problems with the data quality in one of the studies, possibly due to...

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Detalles Bibliográficos
Autores principales: Wall, Jeffrey D, Kim, Sung K
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014787/
https://www.ncbi.nlm.nih.gov/pubmed/17937503
http://dx.doi.org/10.1371/journal.pgen.0030175
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author Wall, Jeffrey D
Kim, Sung K
author_facet Wall, Jeffrey D
Kim, Sung K
author_sort Wall, Jeffrey D
collection PubMed
description Two recently published papers describe nuclear DNA sequences that were obtained from the same Neanderthal fossil. Our reanalyses of the data from these studies show that they are not consistent with each other and point to serious problems with the data quality in one of the studies, possibly due to modern human DNA contaminants and/or a high rate of sequencing errors.
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spelling pubmed-20147872007-10-25 Inconsistencies in Neanderthal Genomic DNA Sequences Wall, Jeffrey D Kim, Sung K PLoS Genet Research Article Two recently published papers describe nuclear DNA sequences that were obtained from the same Neanderthal fossil. Our reanalyses of the data from these studies show that they are not consistent with each other and point to serious problems with the data quality in one of the studies, possibly due to modern human DNA contaminants and/or a high rate of sequencing errors. Public Library of Science 2007-10 2007-10-12 /pmc/articles/PMC2014787/ /pubmed/17937503 http://dx.doi.org/10.1371/journal.pgen.0030175 Text en © 2007 Wall and Kim. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wall, Jeffrey D
Kim, Sung K
Inconsistencies in Neanderthal Genomic DNA Sequences
title Inconsistencies in Neanderthal Genomic DNA Sequences
title_full Inconsistencies in Neanderthal Genomic DNA Sequences
title_fullStr Inconsistencies in Neanderthal Genomic DNA Sequences
title_full_unstemmed Inconsistencies in Neanderthal Genomic DNA Sequences
title_short Inconsistencies in Neanderthal Genomic DNA Sequences
title_sort inconsistencies in neanderthal genomic dna sequences
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014787/
https://www.ncbi.nlm.nih.gov/pubmed/17937503
http://dx.doi.org/10.1371/journal.pgen.0030175
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