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Evolution of Nova-Dependent Splicing Regulation in the Brain

A large number of alternative exons are spliced with tissue-specific patterns, but little is known about how such patterns have evolved. Here, we study the conservation of the neuron-specific splicing factors Nova1 and Nova2 and of the alternatively spliced exons they regulate in mouse brain. Wherea...

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Detalles Bibliográficos
Autores principales: Jelen, Nejc, Ule, Jernej, Živin, Marko, Darnell, Robert B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014790/
https://www.ncbi.nlm.nih.gov/pubmed/17937501
http://dx.doi.org/10.1371/journal.pgen.0030173