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A randomized library approach to identifying functional lox site domains for the Cre recombinase

The bacteriophage P1 Cre/loxP site-specific recombination system is a useful tool in a number of genetic engineering processes. The Cre recombinase has been shown to act on DNA sequences that vary considerably from that of its bacteriophage recognition sequence, loxP. However, little is known about...

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Detalles Bibliográficos
Autores principales: Sheren, Jamie, Langer, Stephen J., Leinwand, Leslie A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018622/
https://www.ncbi.nlm.nih.gov/pubmed/17702764
http://dx.doi.org/10.1093/nar/gkm604