Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair

The Xeroderma Pigmentosum group C (XPC) protein is indispensable to global genomic repair (GGR), a subpathway of nucleotide excision repair (NER), and plays an important role in the initial damage recognition. XPC can be modified by both ubiquitin and SUMO in response to UV irradiation of cells. Her...

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Detalles Bibliográficos
Autores principales: Wang, Qi-En, Prætorius-Ibba, Mette, Zhu, Qianzheng, El-Mahdy, Mohamed A., Wani, Gulzar, Zhao, Qun, Qin, Song, Patnaik, Srinivas, Wani, Altaf A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018625/
https://www.ncbi.nlm.nih.gov/pubmed/17693435
http://dx.doi.org/10.1093/nar/gkm550

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