Protein p56 from the Bacillus subtilis phage ϕ29 inhibits DNA-binding ability of uracil-DNA glycosylase

Protein p56 (56 amino acids) from the Bacillus subtilis phage ϕ29 inactivates the host uracil-DNA glycosylase (UDG), an enzyme involved in the base excision repair pathway. At present, p56 is the only known example of a UDG inhibitor encoded by a non-uracil containing viral DNA. Using analytical ult...

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Detalles Bibliográficos
Autores principales: Serrano-Heras, Gemma, Ruiz-Masó, José A., del Solar, Gloria, Espinosa, Manuel, Bravo, Alicia, Salas, Margarita
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018632/
https://www.ncbi.nlm.nih.gov/pubmed/17698500
http://dx.doi.org/10.1093/nar/gkm584

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