Tissue-specific splicing regulator Fox-1 induces exon skipping by interfering E complex formation on the downstream intron of human F1γ gene

Fox-1 is a regulator of tissue-specific splicing, via binding to the element (U)GCAUG in mRNA precursors, in muscles and neuronal cells. Fox-1 can regulate splicing positively or negatively, most likely depending on where it binds relative to the regulated exon. In cases where the (U)GCAUG element l...

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Detalles Bibliográficos
Autores principales: Fukumura, Kazuhiro, Kato, Ayako, Jin, Yui, Ideue, Takashi, Hirose, Tetsuro, Kataoka, Naoyuki, Fujiwara, Toshinobu, Sakamoto, Hiroshi, Inoue, Kunio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018636/
https://www.ncbi.nlm.nih.gov/pubmed/17686786
http://dx.doi.org/10.1093/nar/gkm569

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