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The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis

BACKGROUND: NOD2, an intracellular pathogen recognition sensor, modulates innate defences to muropeptides derived from various bacterial species, including Mycobacterium tuberculosis (MTB). Experimentally, NOD2 attenuates two key putative mycobactericidal mechanisms. TNF-α synthesis is markedly redu...

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Detalles Bibliográficos
Autores principales:	Lala, Sanjay, Dheda, Keertan, Chang, Jung-Su, Huggett, Jim F, Kim, Louise U, Johnson, Margaret A, Rook, Graham AW, Keshav, Satish, Zumla, Alimuddin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2018706/ https://www.ncbi.nlm.nih.gov/pubmed/17705850 http://dx.doi.org/10.1186/1471-2334-7-96

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