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γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation

BACKGROUND: The histone variant histone H2A.X comprises up to 25% of the H2A complement in mammalian cells. It is rapidly phosphorylated following exposure of cells to double-strand break (DSB) inducing agents such as ionising radiation. Within minutes of DSB generation, H2AX molecules are phosphory...

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Detalles Bibliográficos
Autores principales:	Cowell, Ian G., Sunter, Nicola J., Singh, Prim B., Austin, Caroline A., Durkacz, Barbara W., Tilby, Michael J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020439/ https://www.ncbi.nlm.nih.gov/pubmed/17957241 http://dx.doi.org/10.1371/journal.pone.0001057

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