Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion

Tumors develop through multiple stages, implicating multiple effectors, but the tools to assess how candidate genes contribute to stepwise tumor progression have been limited. We have developed a novel system in which progression of phenotypes in a mouse model of pancreatic islet cell tumorigenesis...

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Detalles Bibliográficos
Autores principales: Du, Yi-Chieh Nancy, Lewis, Brian C, Hanahan, Douglas, Varmus, Harold
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020504/
https://www.ncbi.nlm.nih.gov/pubmed/17941720
http://dx.doi.org/10.1371/journal.pbio.0050276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2020504/
https://www.ncbi.nlm.nih.gov/pubmed/17941720
http://dx.doi.org/10.1371/journal.pbio.0050276

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