Levamisole treatment of local and metastatic growth of transplanted rat tumours.

Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours. The compound did not suppress subcutaneous growth of 3-methylcholanthrene induced sarcomata when administered systemically in a variety of regimens, or when injected in admixtur...

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Detalles Bibliográficos
Autores principales: Hopper, D. G., Pimm, M. V., Baldwin, R. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024738/
https://www.ncbi.nlm.nih.gov/pubmed/1233079
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author Hopper, D. G.
Pimm, M. V.
Baldwin, R. W.
author_facet Hopper, D. G.
Pimm, M. V.
Baldwin, R. W.
author_sort Hopper, D. G.
collection PubMed
description Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours. The compound did not suppress subcutaneous growth of 3-methylcholanthrene induced sarcomata when administered systemically in a variety of regimens, or when injected in admixture with tumour cells. In addition, levamisole treatment failed to suppress pulmonary growth of intravenously transferred sarcoma cells or spontaneous pulmonary metastases appearing after surgical removal of a transplanted epithelioma.
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spelling pubmed-20247382009-09-10 Levamisole treatment of local and metastatic growth of transplanted rat tumours. Hopper, D. G. Pimm, M. V. Baldwin, R. W. Br J Cancer Research Article Levamisole has been examined for its ability to control local growth and pulmonary metastases of transplanted rat tumours. The compound did not suppress subcutaneous growth of 3-methylcholanthrene induced sarcomata when administered systemically in a variety of regimens, or when injected in admixture with tumour cells. In addition, levamisole treatment failed to suppress pulmonary growth of intravenously transferred sarcoma cells or spontaneous pulmonary metastases appearing after surgical removal of a transplanted epithelioma. Nature Publishing Group 1975-09 /pmc/articles/PMC2024738/ /pubmed/1233079 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Hopper, D. G.
Pimm, M. V.
Baldwin, R. W.
Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title_full Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title_fullStr Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title_full_unstemmed Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title_short Levamisole treatment of local and metastatic growth of transplanted rat tumours.
title_sort levamisole treatment of local and metastatic growth of transplanted rat tumours.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024738/
https://www.ncbi.nlm.nih.gov/pubmed/1233079
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AT baldwinrw levamisoletreatmentoflocalandmetastaticgrowthoftransplantedrattumours

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