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Augmentation of cytotoxic drug action and X-irradiation by antibodies.
The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum wherea...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1975
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024752/ https://www.ncbi.nlm.nih.gov/pubmed/1233080 |
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author | Rubens, R. D. Vaughan-Smith, S. Dulbecco, R. |
author_facet | Rubens, R. D. Vaughan-Smith, S. Dulbecco, R. |
author_sort | Rubens, R. D. |
collection | PubMed |
description | The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not. |
format | Text |
id | pubmed-2024752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1975 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20247522009-09-10 Augmentation of cytotoxic drug action and X-irradiation by antibodies. Rubens, R. D. Vaughan-Smith, S. Dulbecco, R. Br J Cancer Research Article The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not. Nature Publishing Group 1975-09 /pmc/articles/PMC2024752/ /pubmed/1233080 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Rubens, R. D. Vaughan-Smith, S. Dulbecco, R. Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title | Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title_full | Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title_fullStr | Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title_full_unstemmed | Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title_short | Augmentation of cytotoxic drug action and X-irradiation by antibodies. |
title_sort | augmentation of cytotoxic drug action and x-irradiation by antibodies. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024752/ https://www.ncbi.nlm.nih.gov/pubmed/1233080 |
work_keys_str_mv | AT rubensrd augmentationofcytotoxicdrugactionandxirradiationbyantibodies AT vaughansmiths augmentationofcytotoxicdrugactionandxirradiationbyantibodies AT dulbeccor augmentationofcytotoxicdrugactionandxirradiationbyantibodies |