Murine leukaemia virus expression in the AKR following thymectomy.

Thymectomy effectively prevents the development of spontaneous lymphoma in the AKR but how this effect is achieved remains to be determined. One possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific...

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Autores principales: Tuffrey, M., Crewe, P., Dawson, L., Holliday, J., Barnes, R. D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024761/
https://www.ncbi.nlm.nih.gov/pubmed/174705
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author Tuffrey, M.
Crewe, P.
Dawson, L.
Holliday, J.
Barnes, R. D.
author_facet Tuffrey, M.
Crewe, P.
Dawson, L.
Holliday, J.
Barnes, R. D.
author_sort Tuffrey, M.
collection PubMed
description Thymectomy effectively prevents the development of spontaneous lymphoma in the AKR but how this effect is achieved remains to be determined. One possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific MuLV antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized AKR.
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spelling pubmed-20247612009-09-10 Murine leukaemia virus expression in the AKR following thymectomy. Tuffrey, M. Crewe, P. Dawson, L. Holliday, J. Barnes, R. D. Br J Cancer Research Article Thymectomy effectively prevents the development of spontaneous lymphoma in the AKR but how this effect is achieved remains to be determined. One possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific MuLV antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized AKR. Nature Publishing Group 1975-10 /pmc/articles/PMC2024761/ /pubmed/174705 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Tuffrey, M.
Crewe, P.
Dawson, L.
Holliday, J.
Barnes, R. D.
Murine leukaemia virus expression in the AKR following thymectomy.
title Murine leukaemia virus expression in the AKR following thymectomy.
title_full Murine leukaemia virus expression in the AKR following thymectomy.
title_fullStr Murine leukaemia virus expression in the AKR following thymectomy.
title_full_unstemmed Murine leukaemia virus expression in the AKR following thymectomy.
title_short Murine leukaemia virus expression in the AKR following thymectomy.
title_sort murine leukaemia virus expression in the akr following thymectomy.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024761/
https://www.ncbi.nlm.nih.gov/pubmed/174705
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