Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.

A simple, rapid histone agglutination test (HAT) is described. It consists of incubation in microplates or in microtubes of blood lymphocytes isolated from cancer patients and patients with non-malignant diseases with microquantities of histone fraction F2A1. Positive reaction is shown by massive ag...

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Autores principales: Sabolović, D., Sabolović, N., Moutte, A., Leibovici, S., Sauvezie, B., Chollet, P., Plagne, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024777/
https://www.ncbi.nlm.nih.gov/pubmed/1058037
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author Sabolović, D.
Sabolović, N.
Moutte, A.
Leibovici, S.
Sauvezie, B.
Chollet, P.
Plagne, R.
author_facet Sabolović, D.
Sabolović, N.
Moutte, A.
Leibovici, S.
Sauvezie, B.
Chollet, P.
Plagne, R.
author_sort Sabolović, D.
collection PubMed
description A simple, rapid histone agglutination test (HAT) is described. It consists of incubation in microplates or in microtubes of blood lymphocytes isolated from cancer patients and patients with non-malignant diseases with microquantities of histone fraction F2A1. Positive reaction is shown by massive agglutination of lymphocytes of the patients tested (126 subjects): this test was positive in 76% of cases. All controls (59 subjects) were negative. IMAGES:
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spelling pubmed-20247772009-09-10 Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction. Sabolović, D. Sabolović, N. Moutte, A. Leibovici, S. Sauvezie, B. Chollet, P. Plagne, R. Br J Cancer Research Article A simple, rapid histone agglutination test (HAT) is described. It consists of incubation in microplates or in microtubes of blood lymphocytes isolated from cancer patients and patients with non-malignant diseases with microquantities of histone fraction F2A1. Positive reaction is shown by massive agglutination of lymphocytes of the patients tested (126 subjects): this test was positive in 76% of cases. All controls (59 subjects) were negative. IMAGES: Nature Publishing Group 1975-07 /pmc/articles/PMC2024777/ /pubmed/1058037 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Sabolović, D.
Sabolović, N.
Moutte, A.
Leibovici, S.
Sauvezie, B.
Chollet, P.
Plagne, R.
Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title_full Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title_fullStr Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title_full_unstemmed Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title_short Agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the F2A1 histone fraction.
title_sort agglutination of peripheral blood lymphocytes from cancer patients and not from healthy controls, with the f2a1 histone fraction.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024777/
https://www.ncbi.nlm.nih.gov/pubmed/1058037
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