Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.

August and Wistar rat lymph node cells were found to respond well to PHA stimulation and in mixed lymphocyte culture, as determined by an increased incorporation of 3H-thymidine. August rat lymph node cells were also stimulated by incubation with irradiated syngeneic tumour cells. Allogeneic Wistar...

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Autores principales: Potter, M. R., Balfour, B. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024779/
https://www.ncbi.nlm.nih.gov/pubmed/126072
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author Potter, M. R.
Balfour, B. M.
author_facet Potter, M. R.
Balfour, B. M.
author_sort Potter, M. R.
collection PubMed
description August and Wistar rat lymph node cells were found to respond well to PHA stimulation and in mixed lymphocyte culture, as determined by an increased incorporation of 3H-thymidine. August rat lymph node cells were also stimulated by incubation with irradiated syngeneic tumour cells. Allogeneic Wistar rat lymph node cells produced a larger response to the August tumour cells. The response of syngeneic and allogeneic lymph node cells was reduced by pretreating the tumour cells with a Wistar anti-tumour serum. Pretreating the tumour cells with sera from normal or tumour bearing rats also reduced the response of syngeneic lymph node cells but did not reduce the response of allogeneic lymph node cells.
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spelling pubmed-20247792009-09-10 Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro. Potter, M. R. Balfour, B. M. Br J Cancer Research Article August and Wistar rat lymph node cells were found to respond well to PHA stimulation and in mixed lymphocyte culture, as determined by an increased incorporation of 3H-thymidine. August rat lymph node cells were also stimulated by incubation with irradiated syngeneic tumour cells. Allogeneic Wistar rat lymph node cells produced a larger response to the August tumour cells. The response of syngeneic and allogeneic lymph node cells was reduced by pretreating the tumour cells with a Wistar anti-tumour serum. Pretreating the tumour cells with sera from normal or tumour bearing rats also reduced the response of syngeneic lymph node cells but did not reduce the response of allogeneic lymph node cells. Nature Publishing Group 1975-07 /pmc/articles/PMC2024779/ /pubmed/126072 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Potter, M. R.
Balfour, B. M.
Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title_full Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title_fullStr Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title_full_unstemmed Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title_short Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
title_sort stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024779/
https://www.ncbi.nlm.nih.gov/pubmed/126072
work_keys_str_mv AT pottermr stimulationofsyngeneicandallogeneiclymphoidcellsbytumourcellsinvitro
AT balfourbm stimulationofsyngeneicandallogeneiclymphoidcellsbytumourcellsinvitro

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