Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.

Good immunoprotection was afforded by A9/SEWA somatic hybrid cells in the C3H mouse/C3H Py tumour system, confirming results previously obtained in the A.SW mouse/SEWA tumour system. However, in this study the immunogenicity decreased with increasing serial subculture of the hybrid line and concomit...

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Detalles Bibliográficos
Autores principales: Favre, R., Carcassonne, Y., Meyer, G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024787/
https://www.ncbi.nlm.nih.gov/pubmed/169867
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author Favre, R.
Carcassonne, Y.
Meyer, G.
author_facet Favre, R.
Carcassonne, Y.
Meyer, G.
author_sort Favre, R.
collection PubMed
description Good immunoprotection was afforded by A9/SEWA somatic hybrid cells in the C3H mouse/C3H Py tumour system, confirming results previously obtained in the A.SW mouse/SEWA tumour system. However, in this study the immunogenicity decreased with increasing serial subculture of the hybrid line and concomitant chromosome loss.
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spelling pubmed-20247872009-09-10 Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture. Favre, R. Carcassonne, Y. Meyer, G. Br J Cancer Research Article Good immunoprotection was afforded by A9/SEWA somatic hybrid cells in the C3H mouse/C3H Py tumour system, confirming results previously obtained in the A.SW mouse/SEWA tumour system. However, in this study the immunogenicity decreased with increasing serial subculture of the hybrid line and concomitant chromosome loss. Nature Publishing Group 1975-07 /pmc/articles/PMC2024787/ /pubmed/169867 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Favre, R.
Carcassonne, Y.
Meyer, G.
Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title_full Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title_fullStr Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title_full_unstemmed Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title_short Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
title_sort loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024787/
https://www.ncbi.nlm.nih.gov/pubmed/169867
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AT meyerg lossofantitumourimmunogenicityofasomaticcellhybridlinewithincreasingsubculture

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