Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.

The extent of binding of 125I-Con A to the surface of SV40-transformed human fibroblasts and the degree of agglutination of the cells by the native lectin have been measured. In addition, trypsinized and succinylated Con A have been used to study the effects of the lectin upon certain cell growth pa...

Descripción completa

Detalles Bibliográficos
Autor principal: Webb, T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024949/
https://www.ncbi.nlm.nih.gov/pubmed/177037
_version_ 1782136664566530048
author Webb, T.
author_facet Webb, T.
author_sort Webb, T.
collection PubMed
description The extent of binding of 125I-Con A to the surface of SV40-transformed human fibroblasts and the degree of agglutination of the cells by the native lectin have been measured. In addition, trypsinized and succinylated Con A have been used to study the effects of the lectin upon certain cell growth parameters. Trypsinized Con A was found to alter the growth rate, the saturation density and the contact inhibition of the transformed cells, an effect not neutralized by alph-methyl-D-mannoside. IMAGES:
format Text
id pubmed-2024949
institution National Center for Biotechnology Information
language English
publishDate 1976
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20249492009-09-10 Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts. Webb, T. Br J Cancer Research Article The extent of binding of 125I-Con A to the surface of SV40-transformed human fibroblasts and the degree of agglutination of the cells by the native lectin have been measured. In addition, trypsinized and succinylated Con A have been used to study the effects of the lectin upon certain cell growth parameters. Trypsinized Con A was found to alter the growth rate, the saturation density and the contact inhibition of the transformed cells, an effect not neutralized by alph-methyl-D-mannoside. IMAGES: Nature Publishing Group 1976-02 /pmc/articles/PMC2024949/ /pubmed/177037 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Webb, T.
Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title_full Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title_fullStr Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title_full_unstemmed Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title_short Studies on the relationship between concanavalin A and SV40-transformed human fibroblasts.
title_sort studies on the relationship between concanavalin a and sv40-transformed human fibroblasts.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024949/
https://www.ncbi.nlm.nih.gov/pubmed/177037
work_keys_str_mv AT webbt studiesontherelationshipbetweenconcanavalinaandsv40transformedhumanfibroblasts

Ejemplares similares