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Neutrophil function in lymphoreticular malignancy.
Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of inf...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1976
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024962/ https://www.ncbi.nlm.nih.gov/pubmed/776198 |
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author | Hancock, B. W. Bruce, L. Richmond, J. |
author_facet | Hancock, B. W. Bruce, L. Richmond, J. |
author_sort | Hancock, B. W. |
collection | PubMed |
description | Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of infections). Candicidal capacity alone was depressed in 7 patients but 4 of these showed depressed cell-mediated immunity to Candida antigen. Splenectomy, radiotherapy and chemotherapy did not alter phagocytic function. |
format | Text |
id | pubmed-2024962 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20249622009-09-10 Neutrophil function in lymphoreticular malignancy. Hancock, B. W. Bruce, L. Richmond, J. Br J Cancer Research Article Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of infections). Candicidal capacity alone was depressed in 7 patients but 4 of these showed depressed cell-mediated immunity to Candida antigen. Splenectomy, radiotherapy and chemotherapy did not alter phagocytic function. Nature Publishing Group 1976-05 /pmc/articles/PMC2024962/ /pubmed/776198 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Hancock, B. W. Bruce, L. Richmond, J. Neutrophil function in lymphoreticular malignancy. |
title | Neutrophil function in lymphoreticular malignancy. |
title_full | Neutrophil function in lymphoreticular malignancy. |
title_fullStr | Neutrophil function in lymphoreticular malignancy. |
title_full_unstemmed | Neutrophil function in lymphoreticular malignancy. |
title_short | Neutrophil function in lymphoreticular malignancy. |
title_sort | neutrophil function in lymphoreticular malignancy. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024962/ https://www.ncbi.nlm.nih.gov/pubmed/776198 |
work_keys_str_mv | AT hancockbw neutrophilfunctioninlymphoreticularmalignancy AT brucel neutrophilfunctioninlymphoreticularmalignancy AT richmondj neutrophilfunctioninlymphoreticularmalignancy |