Cellular localization of immunoglobulin within human maglignant melanomata.

The presence of antibody in patients with malignant melanoma is well established if one examines the serum. In this report we have attempted to identify antibody within solid tumours showing that they are rarely present in any appreciable quantity on the surface of tumour cells but can be seen frequ...

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Detalles Bibliográficos
Autores principales: Lewis, M. G., Proctor, J. W., Thomson, D. M., Rowden, G., Phillips, T. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024991/
https://www.ncbi.nlm.nih.gov/pubmed/773396
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author Lewis, M. G.
Proctor, J. W.
Thomson, D. M.
Rowden, G.
Phillips, T. M.
author_facet Lewis, M. G.
Proctor, J. W.
Thomson, D. M.
Rowden, G.
Phillips, T. M.
author_sort Lewis, M. G.
collection PubMed
description The presence of antibody in patients with malignant melanoma is well established if one examines the serum. In this report we have attempted to identify antibody within solid tumours showing that they are rarely present in any appreciable quantity on the surface of tumour cells but can be seen frequently on a number of different types of host cell within the tumours. This is discussed in the light of the role of antibody in the circulation and the possibility of antibody behaving as a blocking factor in vivo. IMAGES:
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spelling pubmed-20249912009-09-10 Cellular localization of immunoglobulin within human maglignant melanomata. Lewis, M. G. Proctor, J. W. Thomson, D. M. Rowden, G. Phillips, T. M. Br J Cancer Research Article The presence of antibody in patients with malignant melanoma is well established if one examines the serum. In this report we have attempted to identify antibody within solid tumours showing that they are rarely present in any appreciable quantity on the surface of tumour cells but can be seen frequently on a number of different types of host cell within the tumours. This is discussed in the light of the role of antibody in the circulation and the possibility of antibody behaving as a blocking factor in vivo. IMAGES: Nature Publishing Group 1976-03 /pmc/articles/PMC2024991/ /pubmed/773396 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Lewis, M. G.
Proctor, J. W.
Thomson, D. M.
Rowden, G.
Phillips, T. M.
Cellular localization of immunoglobulin within human maglignant melanomata.
title Cellular localization of immunoglobulin within human maglignant melanomata.
title_full Cellular localization of immunoglobulin within human maglignant melanomata.
title_fullStr Cellular localization of immunoglobulin within human maglignant melanomata.
title_full_unstemmed Cellular localization of immunoglobulin within human maglignant melanomata.
title_short Cellular localization of immunoglobulin within human maglignant melanomata.
title_sort cellular localization of immunoglobulin within human maglignant melanomata.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2024991/
https://www.ncbi.nlm.nih.gov/pubmed/773396
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