Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.

Electron microscopic observations of normal BALB/c mouse epidermis revealed the presence of isolated intracisternal A particles. Hyperplasia, papilloma and carcinoma formation induced by topical application of the carcinogenic polycyclic hydrocarbons benz(a)pyrene (B(a)P) and 3-methylcholanthrene (M...

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Detalles Bibliográficos
Autores principales: Bibby, M. C., Smith, G. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025051/
https://www.ncbi.nlm.nih.gov/pubmed/1220759
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author Bibby, M. C.
Smith, G. M.
author_facet Bibby, M. C.
Smith, G. M.
author_sort Bibby, M. C.
collection PubMed
description Electron microscopic observations of normal BALB/c mouse epidermis revealed the presence of isolated intracisternal A particles. Hyperplasia, papilloma and carcinoma formation induced by topical application of the carcinogenic polycyclic hydrocarbons benz(a)pyrene (B(a)P) and 3-methylcholanthrene (MC) is accompanied by an increase in the mumber of A particles. Topical application of a non-carcinogenic irritant alpha-pinene (alpha P) failed to provide comparable changes. Examination of the nuclei indicated occasional electron dense granules in the nucleoplasm which became more common throughout the progression of carcinogenesis. IMAGES:
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spelling pubmed-20250512009-09-10 Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis. Bibby, M. C. Smith, G. M. Br J Cancer Research Article Electron microscopic observations of normal BALB/c mouse epidermis revealed the presence of isolated intracisternal A particles. Hyperplasia, papilloma and carcinoma formation induced by topical application of the carcinogenic polycyclic hydrocarbons benz(a)pyrene (B(a)P) and 3-methylcholanthrene (MC) is accompanied by an increase in the mumber of A particles. Topical application of a non-carcinogenic irritant alpha-pinene (alpha P) failed to provide comparable changes. Examination of the nuclei indicated occasional electron dense granules in the nucleoplasm which became more common throughout the progression of carcinogenesis. IMAGES: Nature Publishing Group 1975-12 /pmc/articles/PMC2025051/ /pubmed/1220759 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Bibby, M. C.
Smith, G. M.
Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title_full Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title_fullStr Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title_full_unstemmed Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title_short Increase in type A virus particles induced in BALB/c mouse epidermis during chemical carcinogenesis.
title_sort increase in type a virus particles induced in balb/c mouse epidermis during chemical carcinogenesis.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025051/
https://www.ncbi.nlm.nih.gov/pubmed/1220759
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AT smithgm increaseintypeavirusparticlesinducedinbalbcmouseepidermisduringchemicalcarcinogenesis

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