DNA polymerase activity in plasma from leukaemic guinea-pigs.

Measurement of DNA polymerase in leukaemic guinea-pig plasms reveals the presence of low levels of sedimentable and non-sedimentable enzymic activities. Since the sedimentable DNA polymerase is ribonuclease sensitive, uses poly(C).oligo(dG) as template, and bands in a sucrose density gradient at 1-1...

Descripción completa

Detalles Bibliográficos
Autores principales: Hallinan, F. M., Maclean, N.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025087/
https://www.ncbi.nlm.nih.gov/pubmed/57790
_version_ 1782136694068215808
author Hallinan, F. M.
Maclean, N.
author_facet Hallinan, F. M.
Maclean, N.
author_sort Hallinan, F. M.
collection PubMed
description Measurement of DNA polymerase in leukaemic guinea-pig plasms reveals the presence of low levels of sedimentable and non-sedimentable enzymic activities. Since the sedimentable DNA polymerase is ribonuclease sensitive, uses poly(C).oligo(dG) as template, and bands in a sucrose density gradient at 1-17 g/ml it is thought to be the GPLV-associated reverse transcriptase. The soluble DNA polymerase is stimulated by ribonuclease and is probably of cellular origin.
format Text
id pubmed-2025087
institution National Center for Biotechnology Information
language English
publishDate 1976
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20250872009-09-10 DNA polymerase activity in plasma from leukaemic guinea-pigs. Hallinan, F. M. Maclean, N. Br J Cancer Research Article Measurement of DNA polymerase in leukaemic guinea-pig plasms reveals the presence of low levels of sedimentable and non-sedimentable enzymic activities. Since the sedimentable DNA polymerase is ribonuclease sensitive, uses poly(C).oligo(dG) as template, and bands in a sucrose density gradient at 1-17 g/ml it is thought to be the GPLV-associated reverse transcriptase. The soluble DNA polymerase is stimulated by ribonuclease and is probably of cellular origin. Nature Publishing Group 1976-04 /pmc/articles/PMC2025087/ /pubmed/57790 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Hallinan, F. M.
Maclean, N.
DNA polymerase activity in plasma from leukaemic guinea-pigs.
title DNA polymerase activity in plasma from leukaemic guinea-pigs.
title_full DNA polymerase activity in plasma from leukaemic guinea-pigs.
title_fullStr DNA polymerase activity in plasma from leukaemic guinea-pigs.
title_full_unstemmed DNA polymerase activity in plasma from leukaemic guinea-pigs.
title_short DNA polymerase activity in plasma from leukaemic guinea-pigs.
title_sort dna polymerase activity in plasma from leukaemic guinea-pigs.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025087/
https://www.ncbi.nlm.nih.gov/pubmed/57790
work_keys_str_mv AT hallinanfm dnapolymeraseactivityinplasmafromleukaemicguineapigs
AT macleann dnapolymeraseactivityinplasmafromleukaemicguineapigs

Ejemplares similares