Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.

Adult mice of strains C3Hf and XVII/G received 2, 4, 5-T by continuous oral administration (80 ppm in the diet). The 2, 4, 5-T preparation contained less than 0-05 ppm of dioxins. In 2, 4, 5-T -treated C3Hf mice a significant increase in the incidence of neoplastic lesions was found. No significant...

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Autores principales: Muranyi-Kovacs, I., Rudali, G., Imbert, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025104/
https://www.ncbi.nlm.nih.gov/pubmed/181042
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author Muranyi-Kovacs, I.
Rudali, G.
Imbert, J.
author_facet Muranyi-Kovacs, I.
Rudali, G.
Imbert, J.
author_sort Muranyi-Kovacs, I.
collection PubMed
description Adult mice of strains C3Hf and XVII/G received 2, 4, 5-T by continuous oral administration (80 ppm in the diet). The 2, 4, 5-T preparation contained less than 0-05 ppm of dioxins. In 2, 4, 5-T -treated C3Hf mice a significant increase in the incidence of neoplastic lesions was found. No significant difference was found in the XVII/G strain between the treated and control mice. Rare forms of tumours, which were not observed in the controls, were present in the 2, 4, 5-t -treated C3Hf mice.
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spelling pubmed-20251042009-09-10 Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice. Muranyi-Kovacs, I. Rudali, G. Imbert, J. Br J Cancer Research Article Adult mice of strains C3Hf and XVII/G received 2, 4, 5-T by continuous oral administration (80 ppm in the diet). The 2, 4, 5-T preparation contained less than 0-05 ppm of dioxins. In 2, 4, 5-T -treated C3Hf mice a significant increase in the incidence of neoplastic lesions was found. No significant difference was found in the XVII/G strain between the treated and control mice. Rare forms of tumours, which were not observed in the controls, were present in the 2, 4, 5-t -treated C3Hf mice. Nature Publishing Group 1976-06 /pmc/articles/PMC2025104/ /pubmed/181042 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Muranyi-Kovacs, I.
Rudali, G.
Imbert, J.
Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title_full Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title_fullStr Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title_full_unstemmed Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title_short Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
title_sort bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025104/
https://www.ncbi.nlm.nih.gov/pubmed/181042
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AT imbertj bioassayof245trichlorophenoxyaceticacidforcarcinogenicityinmice

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