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The multipotential carcinogenic action of N-ethyl-N-nitrosourea administered neonatally to mice.

Newborn A, C57BL, DBAf and IF mice were injected s.c. with a range of doses of N-ethyl-N-nitrosourea (ENU). A high proportion of treated mice developed tumours, particularly hepatomata, pulmonary adenomata and carcinomata, and malignant lymphomata of thymus and spleen. Liver tumours occurred most fr...

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Detalles Bibliográficos
Autores principales: Searle, C. E., Jones, E. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025114/
https://www.ncbi.nlm.nih.gov/pubmed/938611