In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.

Human dialysable Transfer Factor (TFd) extracted from lymphocytes of patients with transitional cell carcinoma of bladder (TCCB) was replicated in culture by lymphoblastoid cell lines. The effectiveness of two such TFdLs produced in vitro in transferring sensitivity to TCCB was assessed in the lymph...

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Autores principales: Pizza, G., Viza, D., Boucheix, C., Corrado, F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025116/
https://www.ncbi.nlm.nih.gov/pubmed/938610
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author Pizza, G.
Viza, D.
Boucheix, C.
Corrado, F.
author_facet Pizza, G.
Viza, D.
Boucheix, C.
Corrado, F.
author_sort Pizza, G.
collection PubMed
description Human dialysable Transfer Factor (TFd) extracted from lymphocytes of patients with transitional cell carcinoma of bladder (TCCB) was replicated in culture by lymphoblastoid cell lines. The effectiveness of two such TFdLs produced in vitro in transferring sensitivity to TCCB was assessed in the lymphocyte migration test (LMT) using formalin-treated TCCB cells as antigen. The results, showed that one TFdL transferred sensitivity in 5/14 cases and the other in 12/15, not only to leucocytes of healthy individuals but also to leucocytes of TCCB patients. Preliminary results showing an in vivo transfer of sensitivity are discussed.
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spelling pubmed-20251162009-09-10 In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder. Pizza, G. Viza, D. Boucheix, C. Corrado, F. Br J Cancer Research Article Human dialysable Transfer Factor (TFd) extracted from lymphocytes of patients with transitional cell carcinoma of bladder (TCCB) was replicated in culture by lymphoblastoid cell lines. The effectiveness of two such TFdLs produced in vitro in transferring sensitivity to TCCB was assessed in the lymphocyte migration test (LMT) using formalin-treated TCCB cells as antigen. The results, showed that one TFdL transferred sensitivity in 5/14 cases and the other in 12/15, not only to leucocytes of healthy individuals but also to leucocytes of TCCB patients. Preliminary results showing an in vivo transfer of sensitivity are discussed. Nature Publishing Group 1976-06 /pmc/articles/PMC2025116/ /pubmed/938610 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Pizza, G.
Viza, D.
Boucheix, C.
Corrado, F.
In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title_full In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title_fullStr In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title_full_unstemmed In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title_short In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
title_sort in vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025116/
https://www.ncbi.nlm.nih.gov/pubmed/938610
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AT vizad invitroproductionofatransferfactorspecificfortransitionalcellcarcinomaofthebladder
AT boucheixc invitroproductionofatransferfactorspecificfortransitionalcellcarcinomaofthebladder
AT corradof invitroproductionofatransferfactorspecificfortransitionalcellcarcinomaofthebladder

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