Cargando…

Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.

In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fe...

Descripción completa

Detalles Bibliográficos
Autores principales: Crowther, J. S., Drasar, B. S., Hill, M. J., Maclennan, R., Magnin, D., Peach, S., Teoh-chan, C. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025151/
https://www.ncbi.nlm.nih.gov/pubmed/962996
_version_ 1782136706623864832
author Crowther, J. S.
Drasar, B. S.
Hill, M. J.
Maclennan, R.
Magnin, D.
Peach, S.
Teoh-chan, C. H.
author_facet Crowther, J. S.
Drasar, B. S.
Hill, M. J.
Maclennan, R.
Magnin, D.
Peach, S.
Teoh-chan, C. H.
author_sort Crowther, J. S.
collection PubMed
description In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fewer eubacteria. Very few of the clostridia able to dehydrogenate the steroid nucleus were isolated. An epidemiological study based on street blocks indicated that the high income group also have a higher incidence of cancer of the large bowel and of the breast. The results are discussed in terms of theories on the aetiology of large bowel cancer.
format Text
id pubmed-2025151
institution National Center for Biotechnology Information
language English
publishDate 1976
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20251512009-09-10 Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. Crowther, J. S. Drasar, B. S. Hill, M. J. Maclennan, R. Magnin, D. Peach, S. Teoh-chan, C. H. Br J Cancer Research Article In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fewer eubacteria. Very few of the clostridia able to dehydrogenate the steroid nucleus were isolated. An epidemiological study based on street blocks indicated that the high income group also have a higher incidence of cancer of the large bowel and of the breast. The results are discussed in terms of theories on the aetiology of large bowel cancer. Nature Publishing Group 1976-08 /pmc/articles/PMC2025151/ /pubmed/962996 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Crowther, J. S.
Drasar, B. S.
Hill, M. J.
Maclennan, R.
Magnin, D.
Peach, S.
Teoh-chan, C. H.
Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title_full Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title_fullStr Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title_full_unstemmed Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title_short Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
title_sort faecal steroids and bacteria and large bowel cancer in hong kong by socio-economic groups.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025151/
https://www.ncbi.nlm.nih.gov/pubmed/962996
work_keys_str_mv AT crowtherjs faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT drasarbs faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT hillmj faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT maclennanr faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT magnind faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT peachs faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups
AT teohchanch faecalsteroidsandbacteriaandlargebowelcancerinhongkongbysocioeconomicgroups