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Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups.
In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fe...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1976
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025151/ https://www.ncbi.nlm.nih.gov/pubmed/962996 |
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author | Crowther, J. S. Drasar, B. S. Hill, M. J. Maclennan, R. Magnin, D. Peach, S. Teoh-chan, C. H. |
author_facet | Crowther, J. S. Drasar, B. S. Hill, M. J. Maclennan, R. Magnin, D. Peach, S. Teoh-chan, C. H. |
author_sort | Crowther, J. S. |
collection | PubMed |
description | In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fewer eubacteria. Very few of the clostridia able to dehydrogenate the steroid nucleus were isolated. An epidemiological study based on street blocks indicated that the high income group also have a higher incidence of cancer of the large bowel and of the breast. The results are discussed in terms of theories on the aetiology of large bowel cancer. |
format | Text |
id | pubmed-2025151 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20251512009-09-10 Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. Crowther, J. S. Drasar, B. S. Hill, M. J. Maclennan, R. Magnin, D. Peach, S. Teoh-chan, C. H. Br J Cancer Research Article In a study of three socio-economic groups in Hong Kong, the high income group had a high faecal concentration of bile acids, especially the dihydroxy bile acids, compared to the low income group. The faecal bile acids were also more highly degraded. The faecal flora contained more bacteroides and fewer eubacteria. Very few of the clostridia able to dehydrogenate the steroid nucleus were isolated. An epidemiological study based on street blocks indicated that the high income group also have a higher incidence of cancer of the large bowel and of the breast. The results are discussed in terms of theories on the aetiology of large bowel cancer. Nature Publishing Group 1976-08 /pmc/articles/PMC2025151/ /pubmed/962996 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Crowther, J. S. Drasar, B. S. Hill, M. J. Maclennan, R. Magnin, D. Peach, S. Teoh-chan, C. H. Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title | Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title_full | Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title_fullStr | Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title_full_unstemmed | Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title_short | Faecal steroids and bacteria and large bowel cancer in Hong Kong by socio-economic groups. |
title_sort | faecal steroids and bacteria and large bowel cancer in hong kong by socio-economic groups. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025151/ https://www.ncbi.nlm.nih.gov/pubmed/962996 |
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