Serum ferritin concentration in untreated Hodgkin's disease.

Serum ferritin has been estimated in 125 untreated patients with Hodgkin's disease. Increasing concentrations are found at each advancing stage of the disease and high concentrations are found in patients with systemic symptoms. In all cases this is associated with a low serum Fe concentration...

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Autores principales: Jacobs, A., Slater, A., Whittaker, J. A., Canellos, G., Wiernik, P. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025167/
https://www.ncbi.nlm.nih.gov/pubmed/962993
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author Jacobs, A.
Slater, A.
Whittaker, J. A.
Canellos, G.
Wiernik, P. H.
author_facet Jacobs, A.
Slater, A.
Whittaker, J. A.
Canellos, G.
Wiernik, P. H.
author_sort Jacobs, A.
collection PubMed
description Serum ferritin has been estimated in 125 untreated patients with Hodgkin's disease. Increasing concentrations are found at each advancing stage of the disease and high concentrations are found in patients with systemic symptoms. In all cases this is associated with a low serum Fe concentration and reduced transferrin saturation. There is no relationship between serum ferritin concentration and histological type of disease. The findings are compatible with a non-specific response of the reticuloendothelial system to malignancy, producing a secondary disorder of Fe metabolism.
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spelling pubmed-20251672009-09-10 Serum ferritin concentration in untreated Hodgkin's disease. Jacobs, A. Slater, A. Whittaker, J. A. Canellos, G. Wiernik, P. H. Br J Cancer Research Article Serum ferritin has been estimated in 125 untreated patients with Hodgkin's disease. Increasing concentrations are found at each advancing stage of the disease and high concentrations are found in patients with systemic symptoms. In all cases this is associated with a low serum Fe concentration and reduced transferrin saturation. There is no relationship between serum ferritin concentration and histological type of disease. The findings are compatible with a non-specific response of the reticuloendothelial system to malignancy, producing a secondary disorder of Fe metabolism. Nature Publishing Group 1976-08 /pmc/articles/PMC2025167/ /pubmed/962993 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Jacobs, A.
Slater, A.
Whittaker, J. A.
Canellos, G.
Wiernik, P. H.
Serum ferritin concentration in untreated Hodgkin's disease.
title Serum ferritin concentration in untreated Hodgkin's disease.
title_full Serum ferritin concentration in untreated Hodgkin's disease.
title_fullStr Serum ferritin concentration in untreated Hodgkin's disease.
title_full_unstemmed Serum ferritin concentration in untreated Hodgkin's disease.
title_short Serum ferritin concentration in untreated Hodgkin's disease.
title_sort serum ferritin concentration in untreated hodgkin's disease.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025167/
https://www.ncbi.nlm.nih.gov/pubmed/962993
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AT canellosg serumferritinconcentrationinuntreatedhodgkinsdisease
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