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Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells.
The i.v. injection of a specified number of cells of either an Ehrlich ascites tumour (ELD) or spontaneous mouse mammary adenocarcinomas (MA) into C3H mice yielded a number of lung colonies which varied significantly with the age or sex of recipient mice. The yield was higher in mice of 71 weeks tha...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1976
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025200/ https://www.ncbi.nlm.nih.gov/pubmed/999785 |
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author | Thompson, S. C. |
author_facet | Thompson, S. C. |
author_sort | Thompson, S. C. |
collection | PubMed |
description | The i.v. injection of a specified number of cells of either an Ehrlich ascites tumour (ELD) or spontaneous mouse mammary adenocarcinomas (MA) into C3H mice yielded a number of lung colonies which varied significantly with the age or sex of recipient mice. The yield was higher in mice of 71 weeks than in those of 15 weeks, except for MA cells injected into females, when the yield was higher in the younger mice. Sex did not influence very significantly the yield of colonies from ELD cells; in the case of MA cells the direction of sex differences depended on age. A difference in the effect of pre-immunization with age was not observed. |
format | Text |
id | pubmed-2025200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20252002009-09-10 Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. Thompson, S. C. Br J Cancer Research Article The i.v. injection of a specified number of cells of either an Ehrlich ascites tumour (ELD) or spontaneous mouse mammary adenocarcinomas (MA) into C3H mice yielded a number of lung colonies which varied significantly with the age or sex of recipient mice. The yield was higher in mice of 71 weeks than in those of 15 weeks, except for MA cells injected into females, when the yield was higher in the younger mice. Sex did not influence very significantly the yield of colonies from ELD cells; in the case of MA cells the direction of sex differences depended on age. A difference in the effect of pre-immunization with age was not observed. Nature Publishing Group 1976-11 /pmc/articles/PMC2025200/ /pubmed/999785 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Thompson, S. C. Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title | Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title_full | Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title_fullStr | Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title_full_unstemmed | Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title_short | Effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
title_sort | effect of age and sex on lung-colony-forming efficiency of injected mouse tumour cells. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025200/ https://www.ncbi.nlm.nih.gov/pubmed/999785 |
work_keys_str_mv | AT thompsonsc effectofageandsexonlungcolonyformingefficiencyofinjectedmousetumourcells |