Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.

Peripheral lymphocyte counts were performed on 41 patients with advanced breast cancer, before starting treatment with oestrogens or androgens. Patients were seen at monthly intervals, and the response to treatment was independently assessed, using the criteria of the British Breast Group. In the pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Franks, C. R., Williams, Y.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025224/
https://www.ncbi.nlm.nih.gov/pubmed/1008991
_version_ 1782136721112039424
author Franks, C. R.
Williams, Y.
author_facet Franks, C. R.
Williams, Y.
author_sort Franks, C. R.
collection PubMed
description Peripheral lymphocyte counts were performed on 41 patients with advanced breast cancer, before starting treatment with oestrogens or androgens. Patients were seen at monthly intervals, and the response to treatment was independently assessed, using the criteria of the British Breast Group. In the patients treated with oestrogens and androgens, the successful responders were found to have significantly higher pre-treatment peripheral lymphocyte counts than the intermediate responders and failures. It is suggested that pre-treatment peripheral lymphocyte counts may have a prognostic value in assessing potential response to hormone therapy in patients with breast cancer.
format Text
id pubmed-2025224
institution National Center for Biotechnology Information
language English
publishDate 1976
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20252242009-09-10 Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer. Franks, C. R. Williams, Y. Br J Cancer Research Article Peripheral lymphocyte counts were performed on 41 patients with advanced breast cancer, before starting treatment with oestrogens or androgens. Patients were seen at monthly intervals, and the response to treatment was independently assessed, using the criteria of the British Breast Group. In the patients treated with oestrogens and androgens, the successful responders were found to have significantly higher pre-treatment peripheral lymphocyte counts than the intermediate responders and failures. It is suggested that pre-treatment peripheral lymphocyte counts may have a prognostic value in assessing potential response to hormone therapy in patients with breast cancer. Nature Publishing Group 1976-12 /pmc/articles/PMC2025224/ /pubmed/1008991 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Franks, C. R.
Williams, Y.
Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title_full Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title_fullStr Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title_full_unstemmed Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title_short Prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
title_sort prognostic value of peripheral lymphocyte count in hormone therapy of advanced breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025224/
https://www.ncbi.nlm.nih.gov/pubmed/1008991
work_keys_str_mv AT frankscr prognosticvalueofperipherallymphocytecountinhormonetherapyofadvancedbreastcancer
AT williamsy prognosticvalueofperipherallymphocytecountinhormonetherapyofadvancedbreastcancer

Ejemplares similares