A monkey antigen crossreacting with carcinoembryonic antigen, CEA.

Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusi...

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Detalles Bibliográficos
Autores principales: Engvall, E., Vuento, M., Ruoslahti, E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1976
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025255/
https://www.ncbi.nlm.nih.gov/pubmed/823952
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author Engvall, E.
Vuento, M.
Ruoslahti, E.
author_facet Engvall, E.
Vuento, M.
Ruoslahti, E.
author_sort Engvall, E.
collection PubMed
description Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusion against anti-CEA or anti-NCA. Extracts of monkey tissues inhibited in radioimmunoassays measuring human NCA. It is possible that monkey foetuses and colonic tumours contain CEA. IMAGES:
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spelling pubmed-20252552009-09-10 A monkey antigen crossreacting with carcinoembryonic antigen, CEA. Engvall, E. Vuento, M. Ruoslahti, E. Br J Cancer Research Article Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusion against anti-CEA or anti-NCA. Extracts of monkey tissues inhibited in radioimmunoassays measuring human NCA. It is possible that monkey foetuses and colonic tumours contain CEA. IMAGES: Nature Publishing Group 1976-10 /pmc/articles/PMC2025255/ /pubmed/823952 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Engvall, E.
Vuento, M.
Ruoslahti, E.
A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title_full A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title_fullStr A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title_full_unstemmed A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title_short A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
title_sort monkey antigen crossreacting with carcinoembryonic antigen, cea.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025255/
https://www.ncbi.nlm.nih.gov/pubmed/823952
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