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Effect of hyperthermia on differential cytotoxicity of a hypoxic cell radiosensitizer, Ro-07-0582, on mammalian cells in vitro.
There is now evidence that several classes of nitro compounds which have been used as radiosensitizers also function as cytotoxic agents specific for hypoxic cells. The 2-nitroimidazole, Ro-07-0582, (1-(2-nitroimidazol-1-yl)-3-methoxy-2-propanol) is a compound of this type, and its effectiveness as...
Autores principales: | Stratford, I. J., Adams, G. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1977
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025287/ https://www.ncbi.nlm.nih.gov/pubmed/856238 |
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