Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.

The aetiologic fractions due to smoking and chewing tobacco have been quantified for the first time, for cancers of the oral cavity, oropharynx, hypopharynx, larynx and oesophagus. The overall aetiologic fractions due to smoking and/or chewing tobacco have been found to be 70% for cancer of the oral...

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Autores principales: Jayant, K., Balakrishnan, V., Sanghvi, L. D., Jussawalla, D. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025317/
https://www.ncbi.nlm.nih.gov/pubmed/836760
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author Jayant, K.
Balakrishnan, V.
Sanghvi, L. D.
Jussawalla, D. J.
author_facet Jayant, K.
Balakrishnan, V.
Sanghvi, L. D.
Jussawalla, D. J.
author_sort Jayant, K.
collection PubMed
description The aetiologic fractions due to smoking and chewing tobacco have been quantified for the first time, for cancers of the oral cavity, oropharynx, hypopharynx, larynx and oesophagus. The overall aetiologic fractions due to smoking and/or chewing tobacco have been found to be 70% for cancer of the oral cavity, 84% for the oropharynx, and about 75% for the hypopharynx and larynx. In cancer of the oesophagus, however, the fraction is only 50%, showing that another factor or factors play an equal role in the aetiology of cancer of this site. At each of the sites studied, it was found that the two factors, smoking and chewing, acted synergistically, though in varying degrees.
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spelling pubmed-20253172009-09-10 Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers. Jayant, K. Balakrishnan, V. Sanghvi, L. D. Jussawalla, D. J. Br J Cancer Research Article The aetiologic fractions due to smoking and chewing tobacco have been quantified for the first time, for cancers of the oral cavity, oropharynx, hypopharynx, larynx and oesophagus. The overall aetiologic fractions due to smoking and/or chewing tobacco have been found to be 70% for cancer of the oral cavity, 84% for the oropharynx, and about 75% for the hypopharynx and larynx. In cancer of the oesophagus, however, the fraction is only 50%, showing that another factor or factors play an equal role in the aetiology of cancer of this site. At each of the sites studied, it was found that the two factors, smoking and chewing, acted synergistically, though in varying degrees. Nature Publishing Group 1977-02 /pmc/articles/PMC2025317/ /pubmed/836760 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Jayant, K.
Balakrishnan, V.
Sanghvi, L. D.
Jussawalla, D. J.
Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title_full Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title_fullStr Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title_full_unstemmed Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title_short Quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
title_sort quantification of the role of smoking and chewing tobacco in oral, pharyngeal, and oesophageal cancers.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025317/
https://www.ncbi.nlm.nih.gov/pubmed/836760
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