A new cell line from a human chondrosarcoma.

Morphological and growth characteristics are described of a rapidly growing cell line with epithelioid and giant-cell characteristics derived from a chondrosarcoma in a male patient 65 years of age. This cell line is of considerable interest because in these cells cross-reacting antigens with known...

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Autores principales: de Man, J. C., Snoep, M. P., Huiskens-van der Meij, J. W., Warnaar, S. O., Schaberg, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025358/
https://www.ncbi.nlm.nih.gov/pubmed/857824
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author de Man, J. C.
Snoep, M. P.
Huiskens-van der Meij, J. W.
Warnaar, S. O.
Schaberg, A.
author_facet de Man, J. C.
Snoep, M. P.
Huiskens-van der Meij, J. W.
Warnaar, S. O.
Schaberg, A.
author_sort de Man, J. C.
collection PubMed
description Morphological and growth characteristics are described of a rapidly growing cell line with epithelioid and giant-cell characteristics derived from a chondrosarcoma in a male patient 65 years of age. This cell line is of considerable interest because in these cells cross-reacting antigens with known animal oncorna-viruses are present. Biochemically, the cells contain particles with a density of 1-16 with "cores" of density 1'23 associated with a reverse-transcriptase-like enzyme and with 70S RNA. Occasionally, virus-like particles were demonstrated by electron microscope in material derived from the culture medium. IMAGES:
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spelling pubmed-20253582009-09-10 A new cell line from a human chondrosarcoma. de Man, J. C. Snoep, M. P. Huiskens-van der Meij, J. W. Warnaar, S. O. Schaberg, A. Br J Cancer Research Article Morphological and growth characteristics are described of a rapidly growing cell line with epithelioid and giant-cell characteristics derived from a chondrosarcoma in a male patient 65 years of age. This cell line is of considerable interest because in these cells cross-reacting antigens with known animal oncorna-viruses are present. Biochemically, the cells contain particles with a density of 1-16 with "cores" of density 1'23 associated with a reverse-transcriptase-like enzyme and with 70S RNA. Occasionally, virus-like particles were demonstrated by electron microscope in material derived from the culture medium. IMAGES: Nature Publishing Group 1977-04 /pmc/articles/PMC2025358/ /pubmed/857824 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
de Man, J. C.
Snoep, M. P.
Huiskens-van der Meij, J. W.
Warnaar, S. O.
Schaberg, A.
A new cell line from a human chondrosarcoma.
title A new cell line from a human chondrosarcoma.
title_full A new cell line from a human chondrosarcoma.
title_fullStr A new cell line from a human chondrosarcoma.
title_full_unstemmed A new cell line from a human chondrosarcoma.
title_short A new cell line from a human chondrosarcoma.
title_sort new cell line from a human chondrosarcoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025358/
https://www.ncbi.nlm.nih.gov/pubmed/857824
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