Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer

A series of patients with a variety of histopathologically confirmed cancers have been examined using the MOD-MEM test as described by Pritchard et al. (1973). Despite the closest possible adherence to the experimental protocols recommended by these authors, no positive reactions to the test were ob...

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Detalles Bibliográficos
Autores principales: Forrester, J. A., Dando, P. M., Smith, W. J., Turberville, C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025385/
Descripción
Sumario:A series of patients with a variety of histopathologically confirmed cancers have been examined using the MOD-MEM test as described by Pritchard et al. (1973). Despite the closest possible adherence to the experimental protocols recommended by these authors, no positive reactions to the test were observed in this series: neither were we able to demonstrate the release of a “macrophage-slowing factor” by a panel of normal donors when challenged with tubercle PPD. We conclude that the test has no present application to the diagnosis of cancer.

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