Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer

A series of patients with a variety of histopathologically confirmed cancers have been examined using the MOD-MEM test as described by Pritchard et al. (1973). Despite the closest possible adherence to the experimental protocols recommended by these authors, no positive reactions to the test were ob...

Descripción completa

Detalles Bibliográficos
Autores principales: Forrester, J. A., Dando, P. M., Smith, W. J., Turberville, C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025385/
_version_ 1782136753225728000
author Forrester, J. A.
Dando, P. M.
Smith, W. J.
Turberville, C.
author_facet Forrester, J. A.
Dando, P. M.
Smith, W. J.
Turberville, C.
author_sort Forrester, J. A.
collection PubMed
description A series of patients with a variety of histopathologically confirmed cancers have been examined using the MOD-MEM test as described by Pritchard et al. (1973). Despite the closest possible adherence to the experimental protocols recommended by these authors, no positive reactions to the test were observed in this series: neither were we able to demonstrate the release of a “macrophage-slowing factor” by a panel of normal donors when challenged with tubercle PPD. We conclude that the test has no present application to the diagnosis of cancer.
format Text
id pubmed-2025385
institution National Center for Biotechnology Information
language English
publishDate 1977
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20253852009-09-10 Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer Forrester, J. A. Dando, P. M. Smith, W. J. Turberville, C. Br J Cancer Articles A series of patients with a variety of histopathologically confirmed cancers have been examined using the MOD-MEM test as described by Pritchard et al. (1973). Despite the closest possible adherence to the experimental protocols recommended by these authors, no positive reactions to the test were observed in this series: neither were we able to demonstrate the release of a “macrophage-slowing factor” by a panel of normal donors when challenged with tubercle PPD. We conclude that the test has no present application to the diagnosis of cancer. Nature Publishing Group 1977-11 /pmc/articles/PMC2025385/ Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Forrester, J. A.
Dando, P. M.
Smith, W. J.
Turberville, C.
Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title_full Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title_fullStr Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title_full_unstemmed Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title_short Failure to Confirm the Macrophage Electrophoretic Mobility Test in Cancer
title_sort failure to confirm the macrophage electrophoretic mobility test in cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025385/
work_keys_str_mv AT forresterja failuretoconfirmthemacrophageelectrophoreticmobilitytestincancer
AT dandopm failuretoconfirmthemacrophageelectrophoreticmobilitytestincancer
AT smithwj failuretoconfirmthemacrophageelectrophoreticmobilitytestincancer
AT turbervillec failuretoconfirmthemacrophageelectrophoreticmobilitytestincancer

Ejemplares similares