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A test for mutation theory of cancer: carcinogenesis by misrepair of DNA damaged by 4-nitroquinoline 1-oxide.

Evidence for a mutation theory of cancer is presented by reviewing the experimental work on 4-nitroquinoline 1-oxide (4NQO) carcinogenesis. 4NQO almost completely mimics u.v. light and produces 4NQO-purine adducts on DNA. When 4NQO-treated cells are held in liquid medium under appropriate conditions...

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Detalles Bibliográficos
Autor principal:	Kondo, S.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1977
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025485/ https://www.ncbi.nlm.nih.gov/pubmed/405031

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