Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.

Patients with acute lymphatic leukaemia (ALL) could be divided into two groups at diagnosis--those whose peripheral blood and/or bone marrow exhibited in vitro colony formation and those in whom it did not, but this finding did not appear to correlate with any clinical or haematological parameter, o...

Descripción completa

Detalles Bibliográficos
Autores principales: Morris, T. C., Butler, M., Muldrew, J. G., McNeill, T. A., Bridges, J. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1977
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025522/
https://www.ncbi.nlm.nih.gov/pubmed/266948
_version_ 1782136780728827904
author Morris, T. C.
Butler, M.
Muldrew, J. G.
McNeill, T. A.
Bridges, J. M.
author_facet Morris, T. C.
Butler, M.
Muldrew, J. G.
McNeill, T. A.
Bridges, J. M.
author_sort Morris, T. C.
collection PubMed
description Patients with acute lymphatic leukaemia (ALL) could be divided into two groups at diagnosis--those whose peripheral blood and/or bone marrow exhibited in vitro colony formation and those in whom it did not, but this finding did not appear to correlate with any clinical or haematological parameter, or with prognosis.The colonly-forming potential of patients with ALL in their first full remission, early relapse or second remission did not deviate significantly from previously established normal values, but the colony-forming potential of patients in early remission was very significantly reduced. No loss of colony-forming potential of normal marrow cells was noted when they were cultured with cells from patients with ALL.
format Text
id pubmed-2025522
institution National Center for Biotechnology Information
language English
publishDate 1977
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20255222009-09-10 Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia. Morris, T. C. Butler, M. Muldrew, J. G. McNeill, T. A. Bridges, J. M. Br J Cancer Research Article Patients with acute lymphatic leukaemia (ALL) could be divided into two groups at diagnosis--those whose peripheral blood and/or bone marrow exhibited in vitro colony formation and those in whom it did not, but this finding did not appear to correlate with any clinical or haematological parameter, or with prognosis.The colonly-forming potential of patients with ALL in their first full remission, early relapse or second remission did not deviate significantly from previously established normal values, but the colony-forming potential of patients in early remission was very significantly reduced. No loss of colony-forming potential of normal marrow cells was noted when they were cultured with cells from patients with ALL. Nature Publishing Group 1977-06 /pmc/articles/PMC2025522/ /pubmed/266948 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Morris, T. C.
Butler, M.
Muldrew, J. G.
McNeill, T. A.
Bridges, J. M.
Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title_full Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title_fullStr Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title_full_unstemmed Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title_short Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
title_sort changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2025522/
https://www.ncbi.nlm.nih.gov/pubmed/266948
work_keys_str_mv AT morristc changesingranulopoiesisdetectedbyinvitrocolonyformationinacutelymphaticleukaemia
AT butlerm changesingranulopoiesisdetectedbyinvitrocolonyformationinacutelymphaticleukaemia
AT muldrewjg changesingranulopoiesisdetectedbyinvitrocolonyformationinacutelymphaticleukaemia
AT mcneillta changesingranulopoiesisdetectedbyinvitrocolonyformationinacutelymphaticleukaemia
AT bridgesjm changesingranulopoiesisdetectedbyinvitrocolonyformationinacutelymphaticleukaemia

Ejemplares similares