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Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study.
A death certificate-based case-control study was conducted on 207 women aged 25-44 who died of bladder cancer in England and Wales in the period 1971-89 and 411 controls matched on sex, year of death and age at death. An odds ratio of 12.0 (95% CI 1.5-99.7) was found for women with a history of para...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033322/ https://www.ncbi.nlm.nih.gov/pubmed/8018530 |
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author | Dolin, P. J. Darby, S. C. Beral, V. |
author_facet | Dolin, P. J. Darby, S. C. Beral, V. |
author_sort | Dolin, P. J. |
collection | PubMed |
description | A death certificate-based case-control study was conducted on 207 women aged 25-44 who died of bladder cancer in England and Wales in the period 1971-89 and 411 controls matched on sex, year of death and age at death. An odds ratio of 12.0 (95% CI 1.5-99.7) was found for women with a history of paraplegia. Four of the six paraplegic women were reported to have had squamous cell carcinoma of the bladder compared with only 19 of the 201 non-paraplegic women. These findings suggest that squamous cell carcinomas of the bladder, especially in paraplegics, may be the result of chronic urinary tract infection. |
format | Text |
id | pubmed-2033322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1994 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20333222009-09-10 Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. Dolin, P. J. Darby, S. C. Beral, V. Br J Cancer Research Article A death certificate-based case-control study was conducted on 207 women aged 25-44 who died of bladder cancer in England and Wales in the period 1971-89 and 411 controls matched on sex, year of death and age at death. An odds ratio of 12.0 (95% CI 1.5-99.7) was found for women with a history of paraplegia. Four of the six paraplegic women were reported to have had squamous cell carcinoma of the bladder compared with only 19 of the 201 non-paraplegic women. These findings suggest that squamous cell carcinomas of the bladder, especially in paraplegics, may be the result of chronic urinary tract infection. Nature Publishing Group 1994-07 /pmc/articles/PMC2033322/ /pubmed/8018530 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Dolin, P. J. Darby, S. C. Beral, V. Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title | Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title_full | Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title_fullStr | Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title_full_unstemmed | Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title_short | Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
title_sort | paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033322/ https://www.ncbi.nlm.nih.gov/pubmed/8018530 |
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