Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?

The retrospective analysis of 250 breast cancer patients with disseminated disease provided evidence that the increase in CA 125 serum levels in these patients was caused by lung metastases or pleural effusions. Seven patients with lung metastases and pleural involvement had elevated CA 125 levels,...

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Detalles Bibliográficos
Autores principales: Jäger, W., Kissing, A., Cilaci, S., Melsheimer, R., Lang, N.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033344/
https://www.ncbi.nlm.nih.gov/pubmed/8080736
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author Jäger, W.
Kissing, A.
Cilaci, S.
Melsheimer, R.
Lang, N.
author_facet Jäger, W.
Kissing, A.
Cilaci, S.
Melsheimer, R.
Lang, N.
author_sort Jäger, W.
collection PubMed
description The retrospective analysis of 250 breast cancer patients with disseminated disease provided evidence that the increase in CA 125 serum levels in these patients was caused by lung metastases or pleural effusions. Seven patients with lung metastases and pleural involvement had elevated CA 125 levels, while in four patients with lung metastases but without pleural effusions CA 125 levels remained normal. In patients with only bone or liver metastases CA 125 levels were usually not elevated. If these results are confirmed, CA 125 would be the first tumour marker in breast cancer whose levels could be associated with one single site of metastases.
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spelling pubmed-20333442009-09-10 Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases? Jäger, W. Kissing, A. Cilaci, S. Melsheimer, R. Lang, N. Br J Cancer Research Article The retrospective analysis of 250 breast cancer patients with disseminated disease provided evidence that the increase in CA 125 serum levels in these patients was caused by lung metastases or pleural effusions. Seven patients with lung metastases and pleural involvement had elevated CA 125 levels, while in four patients with lung metastases but without pleural effusions CA 125 levels remained normal. In patients with only bone or liver metastases CA 125 levels were usually not elevated. If these results are confirmed, CA 125 would be the first tumour marker in breast cancer whose levels could be associated with one single site of metastases. Nature Publishing Group 1994-09 /pmc/articles/PMC2033344/ /pubmed/8080736 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Jäger, W.
Kissing, A.
Cilaci, S.
Melsheimer, R.
Lang, N.
Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title_full Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title_fullStr Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title_full_unstemmed Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title_short Is an increase in CA 125 in breast cancer patients an indicator of pleural metastases?
title_sort is an increase in ca 125 in breast cancer patients an indicator of pleural metastases?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033344/
https://www.ncbi.nlm.nih.gov/pubmed/8080736
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AT melsheimerr isanincreaseinca125inbreastcancerpatientsanindicatorofpleuralmetastases
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