Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.

The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in...

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Autores principales: Adélaide, J., Monges, G., Dérdérian, C., Seitz, J. F., Birnbaum, D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033462/
https://www.ncbi.nlm.nih.gov/pubmed/7819051
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author Adélaide, J.
Monges, G.
Dérdérian, C.
Seitz, J. F.
Birnbaum, D.
author_facet Adélaide, J.
Monges, G.
Dérdérian, C.
Seitz, J. F.
Birnbaum, D.
author_sort Adélaide, J.
collection PubMed
description The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in 54% and overexpressed in 63% of the tumours of the squamous cell type. IMAGES:
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spelling pubmed-20334622009-09-10 Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1. Adélaide, J. Monges, G. Dérdérian, C. Seitz, J. F. Birnbaum, D. Br J Cancer Research Article The human CCND1/PRAD1 gene, located in the 11q13 chromosomal region, encodes a cyclin D protein with potential oncogenic capacity and is involved in several human malignancies. The amplification and expression status of CCND1 was investigated in a series of oesophageal tumours. CCND1 is amplified in 54% and overexpressed in 63% of the tumours of the squamous cell type. IMAGES: Nature Publishing Group 1995-01 /pmc/articles/PMC2033462/ /pubmed/7819051 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Adélaide, J.
Monges, G.
Dérdérian, C.
Seitz, J. F.
Birnbaum, D.
Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title_full Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title_fullStr Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title_full_unstemmed Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title_short Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1.
title_sort oesophageal cancer and amplification of the human cyclin d gene ccnd1/prad1.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033462/
https://www.ncbi.nlm.nih.gov/pubmed/7819051
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