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DT-diaphorase protects cells from the hypoxic cytotoxicity of indoloquinone EO9.
Aerobic sensitivity to indoloquinone EO9 has been shown to correlate with cellular levels of the two-electron reducing enzyme DT-diaphorase. However, little is known about the relative roles of one- and two-electron reducing enzymes in the hypoxic cytotoxicity of EO9. We have characterised a panel o...
Autores principales: | Plumb, J. A., Gerritsen, M., Workman, P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033714/ https://www.ncbi.nlm.nih.gov/pubmed/7526885 |
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