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Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines.
Cisplatin (CDDP) resistance mechanisms were studied in a model of three germ cell tumour and three colon carcinoma cell lines representing intrinsically CDDP-sensitive and -resistant tumours respectively. The CDDP sensitivity of the cell lines mimicked the clinical situation. The glutathione levels...
Autores principales: | Sark, M. W., Timmer-Bosscha, H., Meijer, C., Uges, D. R., Sluiter, W. J., Peters, W. H., Mulder, N. H., de Vries, E. G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033748/ https://www.ncbi.nlm.nih.gov/pubmed/7710929 |
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