Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.

Allelic loss is a common mechanism of inactivation of tumour-suppressor genes in colorectal carcinomas. A number of known or putative tumour-suppressor genes including NF1, BRCA1, NME1, NME2 and prohibitin are present on the long arm of chromosome 17, and this region has not been extensively analyse...

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Detalles Bibliográficos
Autores principales: Leggett, B., Young, J., Buttenshaw, R., Thomas, L., Young, B., Chenevix-Trench, G., Searle, J., Ward, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033787/
https://www.ncbi.nlm.nih.gov/pubmed/7734302

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