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Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.

We examined the microvascular effects of competitive nitric oxide synthase (NOS) inhibition with NG-monomethyl-L-arginine (MeArg), followed by L-arginine, on R3230Ac mammary adenocarcinoma perfusion. In window preparations containing tumours, superfusion of 50 microM MeArg reduced diameters of centr...

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Detalles Bibliográficos
Autores principales: Meyer, R. E., Shan, S., DeAngelo, J., Dodge, R. K., Bonaventura, J., Ong, E. T., Dewhirst, M. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033822/
https://www.ncbi.nlm.nih.gov/pubmed/7540036