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Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.
We examined the microvascular effects of competitive nitric oxide synthase (NOS) inhibition with NG-monomethyl-L-arginine (MeArg), followed by L-arginine, on R3230Ac mammary adenocarcinoma perfusion. In window preparations containing tumours, superfusion of 50 microM MeArg reduced diameters of centr...
Autores principales: | Meyer, R. E., Shan, S., DeAngelo, J., Dodge, R. K., Bonaventura, J., Ong, E. T., Dewhirst, M. W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033822/ https://www.ncbi.nlm.nih.gov/pubmed/7540036 |
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