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Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study.
Many case-control studies have shown that oral contraceptives protect against endometrial cancer and epithelial ovarian cancer, but little information is available from cohort studies. The findings from the Oxford Family Planning Association contraceptive study are reported here; the relative risks...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1995
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033840/ https://www.ncbi.nlm.nih.gov/pubmed/7779735 |
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author | Vessey, M. P. Painter, R. |
author_facet | Vessey, M. P. Painter, R. |
author_sort | Vessey, M. P. |
collection | PubMed |
description | Many case-control studies have shown that oral contraceptives protect against endometrial cancer and epithelial ovarian cancer, but little information is available from cohort studies. The findings from the Oxford Family Planning Association contraceptive study are reported here; the relative risks for ever users of oral contraceptives in comparison with never users were 0.1 (95% confidence interval 0.0-0.7) for endometrial cancer and 0.4 (95% confidence interval 0.2-0.8) for ovarian cancer. There was a strong negative relationship between duration of oral contraceptive use and ovarian cancer risk. Thus, in comparison with never users of oral contraceptives, the relative risk for users of up to 48 months' duration was 1.0 (95% confidence interval 0.4-2.5), while the relative risk for users of 97 months' duration or more was only 0.3 (95% confidence interval 0.1-0.7). |
format | Text |
id | pubmed-2033840 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1995 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20338402009-09-10 Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. Vessey, M. P. Painter, R. Br J Cancer Research Article Many case-control studies have shown that oral contraceptives protect against endometrial cancer and epithelial ovarian cancer, but little information is available from cohort studies. The findings from the Oxford Family Planning Association contraceptive study are reported here; the relative risks for ever users of oral contraceptives in comparison with never users were 0.1 (95% confidence interval 0.0-0.7) for endometrial cancer and 0.4 (95% confidence interval 0.2-0.8) for ovarian cancer. There was a strong negative relationship between duration of oral contraceptive use and ovarian cancer risk. Thus, in comparison with never users of oral contraceptives, the relative risk for users of up to 48 months' duration was 1.0 (95% confidence interval 0.4-2.5), while the relative risk for users of 97 months' duration or more was only 0.3 (95% confidence interval 0.1-0.7). Nature Publishing Group 1995-06 /pmc/articles/PMC2033840/ /pubmed/7779735 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Vessey, M. P. Painter, R. Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title | Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title_full | Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title_fullStr | Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title_full_unstemmed | Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title_short | Endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
title_sort | endometrial and ovarian cancer and oral contraceptives--findings in a large cohort study. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033840/ https://www.ncbi.nlm.nih.gov/pubmed/7779735 |
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