A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage.

The cellular response, in terms of cell cycle arrest(s) and apoptosis, to radiation-induced DNA damage was studied. Experiments were performed on both mitogen-stimulated and resting peripheral blood lymphocytes (PBLs) from normal and cancer-prone (C-P) individuals. The C-P individuals comprised thre...

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Detalles Bibliográficos
Autores principales: Camplejohn, R. S., Perry, P., Hodgson, S. V., Turner, G., Williams, A., Upton, C., MacGeoch, C., Mohammed, S., Barnes, D. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033866/
https://www.ncbi.nlm.nih.gov/pubmed/7669577

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