Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.

In human cervical neoplasia human papillomavirus (HPV) type 18 has a higher cancer/cervical intraepithelial neoplasia (CIN) prevalence ratio than HPV 16. Fibrosarcomas derived from rat fibroblasts transfected with HPV 16 or 18 genomes showed increased apoptosis compared with controls. However, HPV 1...

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Autores principales: Arends, M. J., Wyllie, A. H., Bird, C. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033887/
https://www.ncbi.nlm.nih.gov/pubmed/7669576
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author Arends, M. J.
Wyllie, A. H.
Bird, C. C.
author_facet Arends, M. J.
Wyllie, A. H.
Bird, C. C.
author_sort Arends, M. J.
collection PubMed
description In human cervical neoplasia human papillomavirus (HPV) type 18 has a higher cancer/cervical intraepithelial neoplasia (CIN) prevalence ratio than HPV 16. Fibrosarcomas derived from rat fibroblasts transfected with HPV 16 or 18 genomes showed increased apoptosis compared with controls. However, HPV 18 was associated with significantly less apoptosis than HPV 16, affording one possible explanation for the more rapidly progressive cervical neoplasia associated with HPV 18.
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spelling pubmed-20338872009-09-10 Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16. Arends, M. J. Wyllie, A. H. Bird, C. C. Br J Cancer Research Article In human cervical neoplasia human papillomavirus (HPV) type 18 has a higher cancer/cervical intraepithelial neoplasia (CIN) prevalence ratio than HPV 16. Fibrosarcomas derived from rat fibroblasts transfected with HPV 16 or 18 genomes showed increased apoptosis compared with controls. However, HPV 18 was associated with significantly less apoptosis than HPV 16, affording one possible explanation for the more rapidly progressive cervical neoplasia associated with HPV 18. Nature Publishing Group 1995-09 /pmc/articles/PMC2033887/ /pubmed/7669576 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Arends, M. J.
Wyllie, A. H.
Bird, C. C.
Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title_full Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title_fullStr Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title_full_unstemmed Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title_short Human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
title_sort human papillomavirus type 18 is associated with less apoptosis in fibroblast tumours than human papillomavirus type 16.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033887/
https://www.ncbi.nlm.nih.gov/pubmed/7669576
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